Prescription phosphodiesterase type 5 inhibitors—PDE5 inhibitors—such as sildenafil, tadalafil, vardenafil

PDE5 inhibitors such as sildenafil and tadalafil act directly on the nitric oxide–cGMP erection pathway

FDA has repeatedly warned about sexual enhancement products found to contain undeclared sildenafil, tadalafil

standardized citrulline intervention, and neither should be presented as equivalent to sildenafil, tadalafil

Do not combine sildenafil spray with sildenafil tablets, tadalafil, or other erectile dysfunction medicines

Sildenafil, tadalafil, and other PDE5 inhibitors improve the physical erectile response, particularly